![]() ![]() Likelihood of further events is sought, following MOG-AD diagnosis Clinical/paraclinical features continue to be suggestive of MOG-AD, but MOG antibody.(see “MOG antibody positivity and the diagnosis of MOG-AD: “red flags””) MOG antibody positive, but clinical/paraclinical features not suggestive of MOG-AD.Is unexpectedly poor and clinical/paraclinical features are compatible with MOG-AD Diagnosis of MS is made, interferon beta or natalizumab has been started, but efficacy.Clinical/paraclinical features are suggestive of MOG-AD (2018 International.Neurological update: MOG antibody disease. Wynford-Thomas R, Jacob A, Tomassini V.Phenotype distinct from MS or from neuromyelitis optica (NMO) Subset of patients with antibodies to MOG who express a clinical Neuroinflammatory conditions, has made it possible to identify a Methods for MOG antibody detection using cell-based assays,Īlong with new diagnostic classification of similar The more recent development of highly sensitive and specific.Pathogenic role in CNS inflammatory diseases Years, with some early experimental studies hypothesizing a MOG antibodies have been extensively studied over the last 30.Johns T, Bernard C (1999) The structure and function of myelin oligodendrocyte glycoprotein. J Immunol 139(12):4016–4021īernard C et al (1997) Myelin oligodendrocyte glycoprotein: a novel candidate autoantigen in multiple sclerosis. Schluesener H et al (1987) A monoclonal antibody against a myelin oligodendrocyte glycoprotein induces relapses and demyelination in central nervous system autoimmune disease. Regulator of oligodendrocyte microtubule stability and to Functions: cellular adhesive molecule, to be involved as a.is a glycoprotein located on the myelin surface and foundĮxclusively in the central nervous system (CNS).Myelin oligodendrocyte glycoprotein (MOG). ![]() Myelin Oligodendrocyte Glycoprotein (MOG) Antibody Disease ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |